Contract research reimbursed expenses are project costs paid or incurred by the CRO and billed through to the customer, such as investigator payments, monitoring travel, and other study-specific expenses.
The amounts can be large. Medpace recorded $1.037B of reimbursed out-of-pocket expense in 2025 against $2.530B of total revenue. IQVIA says reimbursed expenses are included in cost of revenues and include investigator payments and clinical-monitor travel.
Pass-through dollars can move revenue faster than service activity
A period with unusually high investigator or other pass-through spending can lift reported revenue even though the CRO's underlying fee economics changed much less.
IQVIA's second-quarter 2026 R&DS revenue grew 8.8% reported, while growth excluding reimbursed expenses was 6.7%. ICON likewise said second-quarter net bookings and revenue benefited from higher pass-through activity.
Accounting presentation still belongs to the issuer
ICON's clinical-trial service accounting treats the full-service obligation, including investigator and other third-party services, as one performance obligation and includes pass-through or reimbursable expenses in the transaction price and cost-based progress measure.
That means investors should not simply strip out every reimbursed dollar from GAAP revenue. The useful task is to understand how pass-through intensity affects growth, book-to-bill, direct costs, and margin interpretation.
Primary sources: Medpace 2025 Form 10-K, IQVIA second-quarter 2026 Form 10-Q, IQVIA second-quarter 2026 results, and ICON 2025 Form 20-F.
Part of the Contract Research Organization Economics
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These companies are examples of how the concept is reported or discussed in public filings. Definitions can differ by issuer; these links open company research rather than a normalized metric comparison.
- ICLROpen operating-model research →6 of 10 reviewed concepts in Contract Research Organization Economics
- IQVOpen operating-model research →8 of 10 reviewed concepts in Contract Research Organization EconomicsPass-through costs and underlying service growth2 of 2 bridge concepts supportedContinue through this bridge:CRO Revenue ex Reimbursements
- MEDPOpen operating-model research →8 of 10 reviewed concepts in Contract Research Organization Economics
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Compare pass-through intensity
Compare reimbursed clinical-trial costs and how investigator payments, travel, and other pass-throughs affect reported revenue, cost, and bookings.
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